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"Medical Association Settles False Advertising Charges Over Promotion of 'Chelation Therapy'" (Press release)

Immunological risks : As a foreign synthetic peptide, it could theoretically provoke immune responses or allergic reactions

Reiniers MJ, van Golen RF, van Gulik TM, Heger M (2014) Reactive oxygen and nitrogen species in steatotic hepatocytes: a molecular perspective on the pathophysiology of ischemia-reperfusion injury in the fatty liver

Because these compounds are naturally occurring peptides with restricted patentability, opportunities for intellectual property protection and industry-sponsored development are limitedposing substantial barriers to the resource-intensive clinical investigations required to confirm therapeutic efficacy and long-term safety

10.3389/fnbeh.2019.00114 72 PopaI.ProtasiewiczD.MunteanC.PopaS