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For primary weight loss in patients with BMI above 30, standard titration to 2.4 mg remains the evidence-based choice per the STEP trial program (Wilding et al., N Engl J Med, 2021)
Study citations, mechanism breakdowns not just marketing copy
It is important to distinguish between a temporary bubble caused by normal medication deposition and other injection site reactions such as localised inflammation, infection, or allergic response
While not always listed among the core eight, GIP serves as a trigger for insulin secretion
Additionally, Wegovy slows gastric emptying, meaning food remains in the stomach longer, which prolongs the sensation of fullness after meals and helps reduce between-meal snacking, though this effect may diminish somewhat over time
