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Whilst vitamin B12 toxicity is exceptionally rare, very high levels from supplements or injections have been associated with skin reactions such as acne-like eruptions

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Vitamin B12 Injections: How They Work Vitamin B12 injections are typically administered through a shot, usually into the muscle, although they can also be given subcutaneously (under the skin)

FRESH - Active Phase (Up to 30 Days) Once reconstituted with bacteriostatic water, immediate refrigeration at 2-8C is required

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Turn the vial upside down and draw the liquid into the syringe