Upregulation of Growth Factors: It increases the expression of receptors for growth factors (like VEGF ), accelerating the rate at which fibroblasts (collagen-producing cells) do their work
New England Journal of Medicine, 393(1), 26-40
Cai J, Chen Y, Seth S, Furukawa S, Compans RW, Jones DP
By your late 40s, most women have early jowling, which occurs because of volume loss in the cheek above (which is why cheek filler can actually remove jowls for women in their 40s and 50s)
Reduced bone mass (osteoporosis) can develop
Sleep optimization for healing Growth hormone release: Deep sleep triggers maximum GH secretion from pituitary