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Deletion of astrocyte connexins 43 and 30 leads to a dysmyelinating phenotype and hippocampal CA1 vacuolation

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This is backed up by another study on brain function, which found that creatine is most likely to exert an influence in situations whereby cognitive processes are stressed. A review suggested that creatine supplementation might also help the brain recover from trauma and shows promise for combating age-related cognitive decline