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This matters enormously for autoimmune patients, many of whom are not overweight and would not qualify for standard GLP-1 prescriptions

Male ob/ob mice were subcutaneously injected with liraglutide daily for 4 weeks, fatty acid synthase (FASN) was down-regulated through the MAPK/ERK and PKA signaling pathways ( in vitro study with peripheral blood mononuclear cells, exendin-4 suppressed inflammatory responses and reduced oxidative stress, which was rmediated by suppressing MAPK signaling pathway (60)

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doi: 10.1056/NEJMoa030204 42 SonMYKimMJYuKKooDBChoYS

Ding L, Zhang J (2012) Glucagon-like peptide-1 activates endothelial nitric oxide synthase in human umbilical vein endothelial cells