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Tabrizi et al., 2020)

Alignment to best practices through use of clinical criteria provides stronger clinical oversight and adherence to appropriate prescribing guidelines

Clinical Trials Demonstrating Reductions in Body Weight with GLP-1RAs Several clinical trials have reported that the effects described above resulted in larger reductions in body weight with GLP-1RA therapy compared with placebo in participants with obesity

Bottom line Semaglutide can cause heartburn or acid reflux, but for most people, its a temporary side effect that improves over time