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In the first study, fasted healthy mice were submitted to an intraperitoneal glucose tolerance test (IPGTT) 5 min after dosing 1 and 14 in order to validate the activity of the reference peptide 1
An HR of 0.79 in favour of orally administered semaglutide compared with placebo was observed, but this 21% reduction in MACE did not reach statistical significance ( p = 0.17 for superiority)
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Have a protein-rich meal within the first few hours, then use GLP-1 compatible protein shakes later in the day when solid food becomes less appealing
& Gorlich, D
Liver Function Studies: Choline and Methionine support methylation and detoxification pathways
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