SARS-CoV-2 induced intestinal responses with a biomimetic human gut-on-chip
A concentration where the target dose falls on a round syringe mark eliminates the mental arithmetic that produces dosing errors
No statement in this article should be interpreted as evidence of clinical efficacy, comprehensive human safety, therapeutic suitability, or regulatory approval
56,57 Accordingly, whether contact-dependent spread reflects a fundamentally distinct transmission mechanism or instead emerges, in part, from density-conditioned membrane architecture remains an important consideration
Other limitations include the fact that the in vitro granuloma model used is not an exact replication of in vivo granulomas which have a more complex and dynamic environment containing other cells like fibroblasts, collagen matrix, and other white blood cells
Holst, J