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Melanocytes: a window into the nervous system
In a primary prevention study among 3,629 cognitively healthy older adults, the Prevention of Alzheimers Disease by Vitamin E and Selenium (PREADViSE) trial, vitamin E supplementation (400 IU/day of supplemental all - rac --tocopheryl acetate [180 mg/day of RRR --tocopherol]) for a mean of 5.4 years had no benefit on prevention of dementia (113)
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If GSH is not fully replenished between attacks, the levels measured during the interictal phase may, in part, reflect the accumulated biochemical footprint of prior attacks rather than any process that is active at the moment of scanning
