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7 A meta-analysis of outcomes data from completed cardiovascular outcome trials suggests that, apart from saxagliptin, DPP-4 inhibitors have a neutral effect on the risk of cardiovascular death, myocardial infarction, stroke and hospitalisation for heart failure

This systemic effect may explain why users sometimes report benefits beyond the specific area being treated

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In particular, recent studies have suggested the role of PS in ferroptosis, which influences the function of the testis, lung, and heart 15

This is a normal part of skin cell turnover, so dont worry if yours does too