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Synthetic liquid medium supplemented with 13 C-labeled methylesterified PGA consisted of 0.67% yeast nitrogen base without amino acids and 0.5% (w/v) 13 C-labeled PGA (1.8% methylester content, 5% 13 C-labeled methylester group)

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Patients with a history of glucose intolerance or uncontrolled diabetes require careful monitoring because elevated GH can affect insulin sensitivity

Research also suggests it may slow cancer growth

Pushing past these limits does not accelerate results and may cause metabolic adaptation