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It optimizes how fat cells store lipids, improves insulin sensitivity, and crucially blunts the severe gastrointestinal nausea typically caused by pure GLP-1 overstimulation

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UTIs are especially common in women due to their shorter urethra, which makes it easier for bacteria to reach the bladder

Patients should be encouraged to report all symptoms to their trial coordinator or supervising clinician, as this contributes to the broader evidence base needed for regulatory assessment

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