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Gastroenterology 162(3):680688

However, despite evidence that glucose promotes alpha cell depolarisation, counter-intuitively, low glucose stimulates glucagon secretion and high glucose inhibits it [34]

10.1002/jnr.10806 78 LazarovO.MorfiniG

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When patients lose weight rapidly they can also lose significant muscle mass, putting them at higher risk for sarcopenic obesity and other long-term health consequences