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Sensitivity analysis reveals the degree of robustness of the results as follows ( Supplementary Figures S3, S4 ): i) Primary outcome & secondary outcomes (nonfatal stroke, all-cause death, HF hospitalization): Excluding any single study did not alter the direction and magnitude of effects, confirming robustness
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A major limitation of the present study is the cross-sectional design of the analyses, which estimated the associations between AC levels and depression at the same assessment (either baseline or 6-year follow-up), precluding conclusions about causality
doi.org/10.3389/fendo.2023.1148556 Unfer V, Facchinetti F, Orr B, Giordani B, Nestler J
Williams LM (2012) Hypothalamic dysfunction in obesity
