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Weight Loss and Maintenance Related to the Mechanism of Action of Glucagon-Like Peptide 1 Receptor Agonists Source In both trials, after 72 weeks of treatment, patients who received Zepbound at all three dose levels experienced a statistically significant reduction in body weight compared to those who received placebo, and greater proportions of patients who received Zepbound achieved at least 5% weight reduction compared to placebo

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2025;69(1):e6

Where GLP-1s Fit in a Healthspan Strategy GLP-1s should not be framed as anti-aging drugs

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Vomiting or diarrhea that prevents fluid intake can become dangerous