Highlighting the potential of this approach, several recent translational and clinical studies beyond the field of MS used this method of delivery and were able to clear intracellular tau pathology in tauopathy mice by intranasal application of an anti-tau-antibody (144) or reduce apathy in frontotemporal dementia patients by intranasal application of oxytocin (149) ( Figure 2C )
The best peptide depends on individual needs, but BPC-157 is known for its healing properties and ability to support recovery
These are established mechanisms at the cell and tissue level
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10.1039/c6fo00773b 113 WangY.WangZ.GaoM.ZhongH.ChenC.YaoY.et al (2019)
This can be due to A oligomers undergoing structural changes because of the extraction method used, thereby artifactual dissociation and formation of oligomers can easily occur before and after analysis in biological fluids and tissue extracts, thus requiring thoroughly interpretation of results (Hayden and Teplow, 2013)
