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Triozzi PL et al

One limitation of this study was the lack of in vivo studies, moreover release studies were performed at the acidic and neutral pH conditions

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Loren Pickart, the researcher who first isolated GHK-Cu, wrote that "the peptide likely acts as a damage signal, alerting the body to a need for repair" rather than as a direct pharmacological agonist

When photosynthetic capacity is overwhelmed, chloroplasts produce elevated levels of ROS, particularly 1 O 2 , leading to lipid peroxidation, chloroplast damage, and irreversible photoinhibition ( Plants have evolved photoprotective mechanisms, including non-photochemical quenching (NPQ) and enzymatic ROS scavenging