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This toxic substance is mainly created as a byproduct during glycolysis
This bivalent effect of aminothiols (pro-oxidant and antioxidant), confirmed for in vitro LDL oxidation (Halvorsen et al, 1996), might explain the discrepancies observed between moderate and severe hyperhomocysteinemia
Kohno H, Tanaka T, Kawabata K, Hirose Y, Sugie S, Tsuda H, Mori H
Glutathione neutralizes ROS and protects muscle cells from oxidative damage
Mice 16 to 20 weeks of age were used in this study
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