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The trial record is summarized in Stier, Vos, and Kenleys 2013 paper

The 4-week minimum at each dose level is not arbitrary

doi: 10.3390/metabo10110450 74 DelijewskiMWrzeniokDOtrbaMBeberokARokJBuszmanE

To verify the functions of these overlapping genes, we conducted KEGG enrichment analysis and found that these genes were significantly enriched in the VEGF signaling pathway, FoxO signaling pathway, MAPK signaling pathway, mTOR signaling pathway, and Wnt signaling pathway (Figure 1B)

10.1111/j.1558-5646.1985.tb00420.x 14 FrearD

Several randomized double-blind clinical trials have been published, evaluating the efficacy of GHK-Cu in topical creams for skin rejuvenation