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What it is / mechanism 5-Amino-1MQ is a selective, cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that methylates nicotinamide (consuming the methyl donor SAM) to form 1-methylnicotinamide, diverting nicotinamide away from the NAD+ salvage pathway
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J Pharmacol Sci (2008) 106(2):1805
329: 97786 Prospective Diabetes Study UK (UKPDS) Group
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