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Most nausea occurs during dose initiation and dose escalation, and it is caused by the slowed gastric emptying that GLP-1 receptor agonists produce
K.JeonY.-J.LeeB.-J.et al (2019)
The 2023 systematic review in Clinical Gastroenterology found that gastroparesis symptoms in GLP-1 users often persisted even after dose reduction or discontinuation, suggesting potential permanent damage to gastric neuromuscular function
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