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About the Author : Trent Fowler has been covering health and wellness for more than a decade
When embarking on a weight loss journey with medications like Semaglutide or Tirzepatide, many people wonder, How long should you stay on Semaglutide or Tirzepatide for lasting weight loss? The key to achieving and maintaining sustainable results lies in understanding the right duration of use for these treatments
For example, long-term starvation induces metabolic depression 102 , which compromises other fitness-related functions and lowers the animals capacity to cope with other stressors 28 , and hence metabolic adaptation is required to ensure survival
Side Effects and Tolerability The side-effect profiles are broadly similar because both medications activate the same receptor pathways
Significant weight loss from GLP-1 therapy may reduce levothyroxine requirements, necessitating regular thyroid function testing every 36 months during active weight loss
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