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the other restores the entire growth hormone cascade that drives sustained, physiological IGF-1 production
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Therefore, gut hormones and vagal afferent neurons have been considered playing an important role in the pathogenesis of obesity (Dockray, Satiety is a result of neuro-humoral stimuli generated during food intake, leading to control of meal size and termination (Woods et al., 1998): thus it is not surprising that an altered sense of satiety has been involved in the pathogenesis of obesity
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