In March 2026, a landmark event took place when the patent for semaglutide, the key active ingredient in many leading diabetes and weight loss drugs, expired in India
Immune checkpoint inhibitors in HBV-caused hepatocellular carcinoma therapy
Nommsen-Rivers LA, Chantry CJ, Peerson JM, Cohen RJ, Dewey KG
It declines with age, and lower NAD+ is associated with slower metabolism and the changes we lump together as getting older. NNMT, meanwhile, consumes the raw materials your body uses to make NAD+ and in fat tissue, NNMT is often overexpressed, which can drag NAD+ down right where you least want a sluggish metabolism
Shen S, Liao Q, Wong YK, et al
KPV anti-inflammatory effects might also allow steroid dose reduction in patients who can achieve adequate inflammation control with peptide supplementation