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For people with chronic obesity and cardiovascular complications, GLP-1 receptor agonists are preferred to amphetamine-based therapies like phentermine, which can worsen blood pressure, heart rate, anxiety, and insomnia

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Food and Drug Administration (FDA) to help manage Type 2 diabetes, these drugs are now also widely prescribed for weight loss, weight management, and cardiovascular health

The precise role of each of these modifications for protein function remains unclear