Legry V, Van Rooyen DM, Lambert B, Sempoux C, Poekes L, Espanol-Suner R, Molendi-Coste O, Horsmans Y, Farrell GC, Leclercq IA
The black box warning for semaglutide is based on animal studies where rats and mice developed thyroid tumors, including a rare type of thyroid cancer called medullary thyroid carcinoma (MTC)
With the advancement of AI, there is growing interest in using machine learning and data analysis techniques to evaluate therapeutic outcomes
Barnard N et al
In the study, 30 adults who had achieved substantial weight loss (~17%) and reached a documented weight plateau on weekly GLP-1 therapy transitioned to reduced-frequency dosing, typically every 10 days to 3 weeks
In one trial, the 25 mg dose led to an average 7% weight loss , while the 50 mg dose led to an average of 15% weight loss