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TOPLINE: The addition of bupropion/naltrexone to glucagon-like peptide 1 (GLP-1) receptor agonists leads to a further 4%-5% total body weight loss (TBWL) in patients with obesity, including those who show a poor response to initial GLP-1 monotherapy

These areas have sufficient subcutaneous fat to ensure the medication is delivered correctly and absorbed efficiently

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None of this literature speaks to that group

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Potential Influence on Clotting Mechanisms The primary concern with semaglutide and blood clots is how it might interact with the bodys natural clotting mechanisms