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Indeed, HGF increases the proliferation of cerebellum granule cell precursors and this effect is reduced in a hypomorphic MET mutant (Grb2-binding incompetent) that leads to a smaller size of the cerebellum (Ieraci et al., 2002)

In human studies, hexarelin at approximately 1 to 2 mcg/kg IV produced plasma GH peaks that were among the highest of any synthetic secretagogue tested at that time, with Ghigo et al

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