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placebo at 52 weeks following weight loss on Wegovy or Zepbound Participants who switched to orforglipron from Wegovy maintained all but 0.9 kg of their previously achieved weight loss on average Lilly has submitted orforglipron to the U.S

In 2021, Wegovy ( semaglutide) became the other GLP-1 approved for weight loss, although its lower-dose sibling Ozempic was approved for diabetes in 2017

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