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Data availability Details of the search strategy and list of identified articles can be found at Abbreviations BGM: Blood glucose monitoring CGM: Continuous glucose monitoring CSII: Continuous subcutaneous insulin infusion CVOT: Cardiovascular outcomes trial DKA: Diabetic ketoacidosis DPP-4i: Dipeptidyl peptidase-4 inhibitors DSMES: Diabetes self-management education and support ETD: Estimated treatment difference GIP: Glucose-dependent insulinotropic polypeptide GLP-1 RA: Glucagon-like peptide-1 receptor agonist(s) HF: Heart failure HHF: Hospitalisation for heart failure MACE: Major adverse cardiovascular events MNT: Medical nutrition therapy NAFLD: Non-alcoholic fatty liver disease NASH: Non-alcoholic steatohepatitis SGLT1i: Sodiumglucose cotransporter-1 inhibitor SGLT2i: Sodiumglucose cotransporter-2 inhibitor(s) TZD: Thiazolidinedione UACR: Urinary albumin/creatinine ratio References Rodriguez-Gutierrez R, Gionfriddo MR, Ospina NS et al (2016) Shared decision making in endocrinology: present and future directions

T.Parts: Water, Glycerin, Dipropylene Glycol, Niacinamide, Phenoxyethanol, PEG-60 Hydrogenated Castor Oil, Chlorphenesin, Carbomer, Triethanolamine, Fragrance, Adenosine, Disodium EDTA, Betaine, Allantoin, 1,2-Hexanediol, Butylene Glycol, Sodium Hyaluronate, Alcohol, Camellia Sinensis Leaf Extract (4ppm), Persea Gratissima (Avocado) Fruit Extract(1ppm), CI 19140, Ethylhexylglycerin, CI 42090, CI 15985

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However the small amount of corticosteroid present in the preparation, doses should be adjusted according to the evolution of the condition and patients response, especially in situations of physical or emotional stress, surgery or injury