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The most common findings in preclinical work are injection-site irritation, transient redness or warmth at the injection site (often associated with GHK-Cu), and copper-zinc balance considerations on longer protocols

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For subcutaneous or intraperitoneal routes in rodent models, saline is well-tolerated and does not require benzyl alcohol exposure

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Curry, S., Mandelkow, H., Brick, P