Care should be taken to ensure that chronic inflammation of persistent skin lesions does not lead to comorbidities, such as arthritis, inflammatory bowel disease (IBD), uveitis, metabolic syndrome, and psychological or psychiatric disorders
Estudios desde los aos 70 (trabajos pioneros de Pickart) documentan efectos en colgeno, elastina, expresin gnica ( ms de 4,000 genes modulados segn anlisis in vitro) y cicatrizacin
If you need something more sustained to lighten the tone, glutathione may be able to help you in the long run
What they do is support the structural integrity of skin that chronic inflammation has damaged
Patel and Shah 2021)
After 24 h, the biofilm was washed once with 1 PBS and imaged using phase contrast microscopy (Zeiss, Axio, Germany), for bacterial adhesion and colonization