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6,7 Semaglutide (GLP1 RA) and tirzepatide (dual glucose-dependent insulinotropic polypeptide (GIP)/GLP1 RA) are the most potent nutrient-stimulated incretin hormone-based therapeutics on the market
While medications like semaglutide target only the GLP-1 receptor, tirzepatide's dual action creates a broader metabolic effect that research has shown produces greater weight loss outcomes in clinical settings
2021;106(3):e1420-e1432
Endocrinology 150 , 33363344 (2009)
Types of GLP-1 Agonists Injectable Formulations Glucagon-like peptide-1 (GLP-1) agonists are primarily available as injectable formulations, administered subcutaneously (under the skin)
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