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Many people entering a Retatrutide protocol expect linear weight loss from week one to week 48

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This is due to slowed gastric emptying, which means the antibiotic stays in your stomach longer before reaching the small intestine where it is absorbed

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Although retatrutide's glucose-dependent mechanism of action is designed to reduce hypoglycaemia risk compared with agents such as sulphonylureas or insulin, the risk is not eliminated particularly when retatrutide is used alongside other glucose-lowering therapies