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Zebrafish for drug toxicity screening: bridging the in vitro cell-based models and in vivo Mammalian models

From telomere maintenance to melatonin regulation, antioxidant defenses, and even tumor suppression, Epitalon presents a compelling narrative backed by molecular evidence

Modeling psychiatric disorders through reprogramming

This evidential gapwhere symptom improvement is confirmed but reproductive benefit remains unknownclearly defines the critical breakthrough direction for future translational research: there is an urgent need to establish a multidimensional evaluation system integrating objective microenvironmental markers (e.g., seminal plasma inflammatory cytokines/oxidative stress markers)semen quality/DFIreproductive outcomes. This is essential to definitively validate the clinical value of microenvironment remodeling interventions in preserving male fertility

Lauer AA, Janitschke D, Dos Santos Guilherme M, Nguyen VTT, Bachmann CM, Qiao S, Schrul B, Boehm U, Grimm HS, Hartmann T, Endres K, Grimm MOW (2021) Shotgun lipidomics of liver and brain tissue of Alzheimers disease model mice treated with acitretin

Vendeville, A