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30 In adolescents with obesity, semaglutide 2.4 mg once weekly led to weight loss similar to that observed in adults (a 16.1% mean reduction in BMI from baseline vs 0.6% with placebo at 68 weeks), along with improvements in cardiometabolic risk factors such as waist circumference, glycated haemoglobin (HbA 1c ), LDL-cholesterol, triglyceride and alanine transaminase levels
Shes an amazingly fit human being, eats sensibly, sleeps well
doi: 10.1016/S2468-1253(17)30285-6, 36
The metabolic benefits continue building without the tolerability challenges of the early weeks
By setting realistic expectations, citing evidence responsibly, and engaging in shared decisionmaking, clinicians can navigate these conversations with confidence
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