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When deficiency is diagnosed, lifelong B replacement is often required (especially in pernicious anemia)

Maintenance Once stores are replete, maintenance is 1mg every two to three months for deficiency of dietary origin, or every two months where there has been neurological involvement

B12 is water-soluble, so it is not stored in fat tissue the way some vitamins are

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Most people feel a genuine lift in energy within about 24 to 72 hours, with the fuller benefits building steadily over the following days and weeks as your levels stabilize

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