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Renal effects, including acute kidney injury, have been reported rarely in post-marketing surveillance, typically in the context of severe gastrointestinal adverse effects leading to dehydration

Big impact

It means that as a standalone oral therapy at the tested doses, it did not produce the magnitude of weight loss that pharmaceutical companies require for commercial viability

Your body responds to these micro-injuries in three phases : Because the epidermis (the outermost layer of skin) remains relatively intact during the procedure, healing time is significantly shorter compared to more aggressive treatments like laser resurfacing or deep chemical peels

The Israel Medical Association Journal

However, the actual results and timeframe can differ significantly from person to person