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In selecting efficacious treatment for people with T2DM and risk of CVD, the ADA/EASD consensus statement notes that both SGLT2i and GLP-1 RA interventions may be appropriate, and recommend determining the existence of established CVD, or the probable risk of developing CVD or CKD

Since price increases in August 2025, theres a notable difference between the two

These effects typically diminish as patients adapt

While direct PCOS studies are ongoing, we can draw meaningful insights from what we know about similar medications

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However, this is an off-label practice, and it is not yet clear whether using sub-clinical doses are either effective or safe