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Circulation 129 (25 Suppl 2), S102S138

They may improve digestion and prevent constipation by supporting a healthy gut

Abbreviations BMI: Body mass index DPP-4is: Dipeptidyl peptidase-4 inhibitors GLP-1 RAs: Glucagon-like peptide-1 receptor agonists HbA1c: Hemoglobin Alc ICERs: Incremental cost-effectiveness ratios PSA: Probabilistic sensitivity analyses QALYs: Quality-adjusted life years SBP: Systolic blood pressure SMPA: Sunshine Medical Procurement All-In-One UKPDS: United Kingdom Prospective Diabetes Studies References International Diabetes Federation

Higher semaglutide doses have shown greater weight loss in trials, but tolerability and persistence become increasingly important

The number of older adults living with diabetes is expected to increase rapidly in the coming decades as the population ages and the effects of increasing obesity rates manifest in this population