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In contrast, obesity reduces the expression of KLB in subcutaneous and visceral adipose tissue ( As an endocrine factor, FGF21 has been shown in preclinical models to exert effects in diverse tissues beyond liver, including adipose tissue, pancreas, skeletal muscle, and the central nervous system

And those industries face fit volatility on two fronts

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Downstream interaction by glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide agonism is required for synergistic effects on body weight

Equipped with this data, we can begin to develop treatments for your specific health needs

Kemeny L, Koreck A, Kis K, et al