Elegant experiments in mice with deletions of the genes for the two incretin hormone receptors have shown that whereas DPP-IV inhibitors effectively lowered blood glucose and stimulated insulin secretion in animals with a single deletion, they had no effect in mice in which both receptor genes were deleted (102)
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And do not take two doses within 72 hours trying to get back on schedule
Side Effects to Consider Both medications are generally well-tolerated, but they can cause mild side effects such as: Nausea Diarrhea Decreased appetite Fatigue These effects are typically temporary and decrease as your body adjusts to the medication
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L-carnitine and acetyl-L-carnitine in human nerves from normal and diabetic subjects