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The patients who received the GLP-1 infusion had a significant improvement in left ventricular ejection fraction, VO2 max, and 6-minute walking distance
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Anti-depressants, which increase BDNF levels, lead to improvements in depressive behavior in BDNF-deletion mutant mice (Taliaz et al., 2010
Thus, it is possible that there is simultaneous secretion of these hormones by gut nutrient stimulation [8]
More Complex Mechanism = More Complex Risks Activating two pathways may have unforeseen interactions GIPs role in gastrointestinal function not fully understood Potential for different or additional side effects beyond GLP-1 alone 3
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