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Behavioural support, dietary guidance, and regular clinical monitoring are all considered best practice within NICE obesity management frameworks (NICE Clinical Guideline CG189)

Liraglutide (Victoza, Saxenda) Blood sugar changes Headache Heartburn Constipation Vomiting Stomach pain Increased feelings of depression Mood changes Phentermine-Topiramate (Qsymia) Changes in taste Tingling, itching, burning, or prickling in your extremities Dry mouth Trouble staying focused Irritability Dizziness Constipation Numbness Headache Naltrexone-Bupropion (Contrave) Orlistat (Xenical) Fatty stools Frequent bowel movements Gassiness Inability to hold in stool Setmelanotide (Imcivree) Are Weight Loss Medications Right for You

fiber, vegetable, and fruit intake remained inadequate, while saturated fat and sodium intake were high [111]

While all GLP-1s effectively reduce HbA1c levels, long-acting weekly GLP-1s like semaglutide and dulaglutide tend to be more effective in reducing fasting glucose and HbA1c levels compared to shorter-acting medications used daily

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Results vary individually, but 89% of tirzepatide users and 69% of semaglutide users lose at least 10% of their body weight