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How to Poop Better if Youre on a GLP-1 Medication Glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound) carry a few well-known side effects, but theres one that often goes overlooked: constipation

One GLP-1 drug worked only briefly

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