Therefore, GLP-1R agonists are currently being intensively studied for their use in the treatment of neurodegenerative diseases such as Alzheimers disease and Parkinsons disease [17, 18]
A 2025 randomized, double-blind, controlled trial published in PLOS ONE found that Ceylon cinnamon extract significantly reduced fasting blood sugar by approximately 8.59mg/dL compared to placebo
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Many downstream target genes of NRF2, such as HO1, SLC7A11, FTH/L, and FPN, are related to the regulation of ferroptosis, suggesting NRF2 is a key negative regulator of ferroptosis [92]