Meet the Meds: GLP-1s and Beyond Ozempic (semaglutide) Approved for: Type 2 diabetes Released in: December 2017 Common use today: Frequently prescribed off-label for weight loss Average weight loss: About 1215% Notable facts: Its weight-loss side effect turned it into a pop-culture phenomenon Wegovy (semaglutide 2.4 mg) Approved for: Chronic weight management Released in: June 2021 Common use today: A go-to GLP-1 medication for obesity Average weight loss: Around 15% Notable facts: Same active ingredient as Ozempic, but approved at higher dosage specifically for weight loss Mounjaro (tirzepatide) Approved for: Type 2 diabetes Released in: May 2022 Common use today: Prescribed for diabetes
While considered a known effect of this therapeutic class, it remains a key monitoring parameter
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During pregnancy, most experts recommend avoiding unregulated IV infusions
Researchers then tracked opioid overdose cases in patients for a year after they discontinued semaglutide or the other diabetes treatments
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