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People taking high-dose B12 supplements (1,000 to 5,000 mcg daily), receiving B12 injections (cyanocobalamin or methylcobalamin), or consuming heavily fortified foods can easily push their serum levels above 900 pg/mL
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This can lead to different kinds of anemia, fatigue, weakness, tingling in the fingers and toes, numbness, irregular heartbeat, mood swings, shortness of breath, very pale skin, memory loss, confusion, and more
Biochemical Pharmacology (2018) 2
Once the immediate deficiency is corrected, the frequency is reduced to weekly and eventually monthly sessions
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