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Disruption of the AMPK-TBC1D1 nexus increases lipogenic gene expression and causes obesity in mice via promoting IGF1 secretion
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It provides a model for investigating how a simple molecule can act as a master regulator, influencing multiple interconnected pathways to shift the overall state of a cell or tissue culture
His first post-doctoral student, John Mayer, directed Lillys peptide research group for over a decade
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